Targeting prostate cancer stem cells with T cell immunotherapy
Presented By:
Amy S. Codd - PhD Student, Cardiff University
Speaker Biography:
I am currently doing a PhD in Cardiff University. I'm investigating if T cell immunotherapy could be used to effectively target cancer stem cells in prostate cancer, in the lab of Zsuzsanna Tabi, as part of the Tissue Microenvironment Group (TMEG). I am funded by Tenovus Cancer Care to carry out this work. I received additional funding from the Great Britain Sasakawa foundation in 2017 to complete collaborative work in Sapporo Medical University, Japan.
Webinar:
Targeting prostate cancer stem cells with T cell immunotherapy
Webinar Abstract:
In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simultaneously maintaining their own population. This enables potentially endless growth and recovery from damage. Cancer stem cells (CSC) sustain cancer growth in the same way as normal stem cells do in healthy tissues. They give rise to both CSC and non-CSC tumour cells, the latter which lack stemness but make up the bulk of a tumour. DNA damaging agents (radiation and chemotherapy) can stop tumour growth by killing non-CSC tumour cells but CSC are resistant to these treatments. Surviving CSC could cause cancer relapse and progression, resulting in higher rates of patient mortality. There is growing interest in developing treatments which are specifically effective against CSC.
Learning Objectives:
-Understand the methods used to identify cancer stem cells
-Learn about the different types of tumour antigen which may be targeted in immunotherapy and how therapeutic antigens are identified
Earn PACE Credits:
1. Make sure you’re a registered member of LabRoots (https://www.labroots.com/ms/we....binar/targeting-pros
2. Watch the webinar on YouTube or on the LabRoots Website (https://www.labroots.com/ms/we....binar/targeting-pros
3. Click Here to get your PACE credits (Expiration date – January 29, 2021 09:00 AM): https://www.labroots.com/credi....t/pace-credits/3210/
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